![]() In this study the rate of healing of granulating wounds on the backs of two species of animals, the rat and the guinea pig, has been studied when supplements of zinc salts were given in association with a normal diet. (8/305)It has now been universally accepted that zinc deficiency interferes in some way with wound healing, but the claims that the addition of zinc supplements to the normally nourished rat accelerates wound healing to super-normal levels has, on investigations, produced contradictory results. ( +info)Įffect of supplements of zinc salts on the healing of granulating wounds in the rat and guinea pig. The results of these studies suggest that supplemental ZnO at 1,500 to 2,000 mg Zn/kg Zn improved postweaning pig performance, and its combination with an antibacterial agent resulted in additional performance improvements. These responses occurred in an additive manner. For the 28-d postweaning period, gains (P < 0.01), feed intakes (P < 0.05), and gain:feed ratios (P < 0.05) increased when dietary ZnO concentrations increased and when carbadox was added. A total of 918 pigs were weaned at an average 19.7 d of age. Carbadox was added at 0 or 55 mg/kg diet, and ZnO was added at 0, 1,500, or 3,000 mg Zn/ kg. The experiment was a 2 x 3 factorial arrangement in a randomized complete block design conducted in a total of 20 replicates. Experiment 2 was conducted at seven stations (KY, MI, MO, NE, ND, OH, and OK) and evaluated the efficacy of an antibacterial agent (carbadox) in combination with added ZnO. The early-weaned pig group had greater (P 1,000 mg Zn/kg. Two Zn metal products, Zn metal dust (100% Zn) and Zn metal fume (91.5% Zn), were also evaluated, and they were found to have Zn RBV values of 67 (P 0.05), but not to PMN influx (1X = 5.5 +/- 1.7 x 10(4), 13.9 +/- 1.7 x 10(4), p 20 d (18 replicates) of age, the two sets of data were analyzed separately. 10) from the standard, but average RBV values for FG Source 2 and FG Source 3 were only 34 (P.10) in RBV from the ZnSO4.7H2O standard. 1 and 2, pigs fed high Zn for wk 1 and 2 or the entire 28-d nursery period had the greatest (P. Dietary Zn treatments were 1) adequate Zn fed wk 1 to 4, 2) high Zn fed wk 1, 3) high Zn fed wk 2, 4) high Zn fed wk 1 and 2, 5) high Zn fed wk 2 and 3, and 6) high Zn fed wk 1 to 4. 1 and 2, respectively, that changed in dietary ingredients and nutrient content (lysine and crude protein) to meet the changing physiological needs of the pigs for the 28-d nursery period. Pigs were fed four or two dietary phases in Exp. 2 (n = 246, 24.5 d of age, 7.2 kg BW), pigs were fed either basal diets containing 100 ppm supplemental Zn (adequate) or the same diet with an additional 3,000 ppm Zn (high) supplied as ZnO. We conducted two experiments to evaluate the effect on growth from feeding 3,000 ppm Zn as ZnO during different weeks of the nursery period. ![]() (1/305)Benefits of feeding pharmacological concentrations of zinc (Zn) provided by Zn oxide (ZnO) to 21-d conventionally weaned pigs in the nursery have been documented however, several management questions remain. Early- and traditionally weaned nursery pigs benefit from phase-feeding pharmacological concentrations of zinc oxide: effect on metallothionein and mineral concentrations. ![]()
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